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Project: Visualizing white matter shape characteristics

Description

Within the field of tractography incredible advancements have been made by being able to non-invasively measure and model nerve tracts within the human body. While this alone allows for a better understanding of the neural pathways, this has also opened the door for further extraction of valuable insights from the resulting geometry using advanced visualization techniques. This project aims to aid complex analyses by constructing three-dimensional maps that visualize and characterize the geometric shape features present.

While this project will build on precomputed streamlines, understanding the modelling and drawbacks of the generated tractograms is still relevant. This project will then apply novel methods for extracting shape features to quantify and characterize geometric aspects of the fibre pathways such as shape, size, and complexity. At any volume of the tractogram, these metrics provide a signature to represent that volume. Further visualization techniques will then be applied to explore these signatures. The result of this project will consist of a tool to explore and analyse a variety of features of the structure of the brain, which can lead to new or improved diagnostic tools for neurological irregularities.

Details
Student
CS
Cas Sievers
Supervisor
Maxime Chamberland