The Center for Infectious Disease Control, RIVM, is the national knowledge center and coordinator in the infectious disease domain. One way of reducing health problems related to infectious diseases is by
vaccination. For some infectious diseases, such as the Human papilloma virus ( HPV) infection and
pneumococcal disease, persons can get infected by multiple variants at the same time. Because vaccination only works against some variants of these diseases, the effect of vaccination on these diseases are
still unclear. Studies are being conducted to investigate this. The information in those studies is quite
complex.
Therefore we designed an interactive exploratory visualization tool, ComboVis. ComboVis can help
epidemiologist answer questions about the data from longitudinal studies concerning multi-variant
diseases. Multiple visualization techniques that are being used for data in a similar format have been
discussed with multiple epidemiologists. Based on the feedback, we combined different visualization
techniques. During the design phase, an early user evaluation was conducted. The feedback from the
early user evaluation is processed in the next version of ComboVis. Finally, another user evaluation with
another group of epidemiologists was conducted, which resulted in enthusiastic and positive reactions
and the final version of ComboVis.